Abstract: Objective To analyze the clinical characteristics of IgA nephropathy and Henoch-Schonlein purpura nephritis in children, and to explore the value of its clinical and pathological classification.Methods Patients with the first onset of the IgA nephropathy or Henoch-Schonlein purpura nephritis , who hospitalized in our hospital from January 2014 to December 2018 were studied retrospectively to summarize their clinical data. The clinical and pathological classification of IgA nephropathy and Henoch-Schonlein was according to the criterion of Kidney Pathology Group of pediatric Branch of Chinese Medical Association.Results There were 255 cases of first IgA nephropathy and 212 cases of Henoch-Schonlein purpura nephritis included in this study. Nephritic syndrome type (45.5% vs 39.2%), hematuria and proteinuria type (41.2% vs 42.5%) were most common, while isolated proteinuria type and chronic nephritis were not seen in both IgA nephropathy and Henoch-Schonlein purpura nephritis group. Grades Ⅲ (52.4%~53.6% vs 51.8%~53.9%) and Ⅱ (35.3%~36.2% vs 34.6%~36.3%) were the most common pathological types in different clinical types (P>0.05). The prognosis between different clinical types was the same (99.1%~100% vs 97.6%~100%) (P>0.05).Conclusion The clinical and pathological classification of childhood IgA nephropathy and Henoch-Schonlein purpura nephritis in China is useless and it should be discussed further.

Key words: Childhood, Classification, Henoch-Schonlein purpura nephritis, IgA nephropathy