Abstract: Objective: To summarize the clinical data of 2 children with simulated vasculitis like artificial dermatitis (DA) and improve the understanding of the disease. Methods: The outpatient and inpatient medical history data of 2 patients were collected, including treatment process, clinical characteristics, relevant laboratory examination and pathological data, and the literature was reviewed. Results: There were 2 patients, 1 male and 1 female. The onset age was 9 and 10 years old respectively. Two patients underwent frequent and repeated examinations at different hospitals. The shape of skin injury was nonspecific, the boundary with normal skin was clear, and it was distributed in the accessible range of both hands and mouth symmetrically.There was no correlation between skin damage and laboratory examination results.Foreign bodies were found in 1 case by skin biopsypathology, and there was no response to drug treatment. Patients denied that skin damage was selfcaused. Conclusion: Artificial dermatitis is rare in children. Although the manifestations of skin damage are nonspecific, they are clearly separated from normal skin and distributed in the accessible range of hands and mouth. The discovery of foreign bodies by skin biopsy is helpful to the diagnosis of the disease. Attention should be paid to the potential mental and psychological problems of children with DA. Multidisciplinary collaboration contributes to the diagnosis and management

Key words: Dermatitis artefacta, Artificial dermatitis, Mental disorder, Psychodermatosis