Chinese Journal of Evidence -Based Pediatric ›› 2017, Vol. 12 ›› Issue (3): 170-174.

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A cross-sectional study of indications of esophageal gastroduodenoscopy in children and the correlation analysis of indications and significant findings

WANG Sheng-nan1), LU Xiao-lan1), CHEN Lian2), HUANG Ying1)   

  1. Children's Hospital of Fudan University, Shanghai 201102, China; 1) Gastroenterology Department, 2) Pathology Department
  • Received:2017-06-25 Revised:2017-06-25 Online:2017-06-25 Published:2017-06-25
  • Contact: HUANG Ying

Abstract:

Objective: An investigation about esophageal gastroduodenoscopy (EGD) was performed, and the association between the symptoms or history and significant findings was analyzed.Methods: This cross-sectional study was conducted through a questionnaire formulated by ourselves. Then we chi-square statistical test and multivariate Logistical regression were used to analyze the correlation between indications and significant findings. Results: The study was conducted from June 10, 2016 to October 7, 2016. And 1 298 cases (male 766) were enrolled. The age was from 0.1 to 17.6 (average age: 8.0±0.01) years. Patients with abdominal pain accounted for 78.0%, then anorexia 31.3%, having breath 24.9%, having evidence for Helicobacter pylori infection 18%, nausea 17%, vomiting 16.7%, having a family history of Helicobacter pylori infection 13.4%. Others were all below 10%. There were 49.9 % having a significant lesion through EGD. Evidence of infection of helicobacter pylori (OR=5.10, 95% CI: 3.58 ~7.28), vomiting (OR=1.48, 95% CI: 1.08~2.04)and suspicious foreign body injection 3.25(95%CI: 1.31~8.02)were related with significant findings. While abdominal pain was related with significant findings (OR=0.73, 95% CI: 0.54~0.98), further investigation was made for abdominal pain. And it was found that the degree value of abdominal pain beyond 5 was related with significant findings (OR=1.37, 95% CI: 1.07~1.74). Conclusion78% of EGD patients are with the complain of abdominal pain. Evidence of infection of helicobacter pylori, vomiting and suspicious foreign body injection are positively related with significant findings. And the degree value of abdominal pain beyond 5 is positively related with significant findings.

Key words: Children, Esophageal gastroduodenoscopy;Indications