Abstract:

objective: To systematically review the effectiveness of music intervention on the regulation of physiological parameters of preterm infants during hospitalization. Methods: Databases including CNKI, WANFANG，Pubmed, CINAHL, Embase and Cochrane Library were electronically searched for the randomized controlled trials(RCTs) on the effect of music intervention on the physiological parameters of hospitalized preterm infants from inception to April 18, 2017. Participants were stable preterm infants with normal hearing. The experimental group was treated with music intervention (without limitation of music type, intervention time, frequency and duration). During the intervention, premature infants did not receive any invasive stimuli, and were in a calm state. The control group did not receive any music intervention. Outcome indicators included oxygen saturation, heart rate, respiratory frequency and other physiological indicators. The methodological quality of the literatures was evaluated by JBI literature quality evaluation tool and data were analyzed by RevMan 5.3 software. Results: A total of nine studies met the inclusion and exclusion criteria, and five of them with quality A or B (all in English) were analyzed. All the five studies reported oxygen saturation, and four reported heart rate and respiratory rate. Metaanalysis showed that the difference of oxygen saturation, heart rate and respiration rate of preterm infants was not statistically significant between the intervention group and the control group. According to the different types of music and different forms of music implementation, subgroup analysis of lullaby, recorded music and live music were conducted. Results showed that the oxygen saturation of the recorded music group was higher than that of the control group ［MD=0.81, 95% CI: 0.03-1.59), Z=2.05, P=0.04］ and there was no significant difference in oxygen saturation, heart rate and respiratory rate between the other subgroups and the control group. Conclusion: The effect of music intervention on regulating the vital signs of premature infants is still unclear. In view of the absence of RCTs with good quality in this field, it is necessary to carry out more largescale and highquality RCTs to further explore the effectiveness of music intervention on physical parameters of hospitalized preterm infants.