Abstract: Objective To summarize the results of 8 cases with bronchopulmonary dysplasia (BPD) for 6 years clinical follow-up study. Methods Eight cases with BPD born at the Affiliated Yuying Children′s Hospital of Wenzhou Medical College from January 2004 to December 2005 were contacted by out-patient follow-up or telephone at the age of 1, 3 and 6 years in order to explore the long-term outcome of BPD. Results Three cases of BPD children were contacted by telephone at 1 year old and 5 cases were contacted by out-patient follow-up at this age. Two cases of BPD children were contacted by telephone at 3 years old and 6 cases were contacted by out-patient follow-up at this age. Eight cases of BPD children were all contacted by out-patient follow-up at 6 years old. The re-hospitalization times were 22, 6 and 1 due to recurrent pneumonia or acute bronchitis at the age of 1, 3 and 6 years, respectively. The wheezing times were 10 (4 cases), 6 (3 cases) and 3 (2 cases) at the age of 1, 3 and 6 years, respectively. Pulmonary function tests showed abnormalities in 5 cases (62.5%), including small airway changes, mild obstructive ventilatory dysfunction, etc. Chest radiography showed ground grass opacity, vesicle formation in 3 cases, thickness or turbulence of texture in bilateral lungs, irregular opacity in 3 cases and local emphysema in 2 cases. Conclusions BPD significantly increased the risk of re-hospitalization after birth. It occurred commonly at the age of 1 year and decreased at pre-school age.Clinical follow-up at the age of 6 years found that 62.5% of the cases showed abnormal pulmonary function,and the characteristics of ground grass opacity, vesicle formation and local emphysema in chest image.