中国循证儿科杂志 ›› 2020, Vol. 15 ›› Issue (1): 59-62.

• 论著 • 上一篇    下一篇

智商大于70的孤独症谱系障碍男女学龄前期儿童 智力结构的病例对照研究

邓晶鑫,燕东雍,徐琼,李慧萍,徐秀   

  1. 复旦大学附属儿科医院 上海,201102
  • 收稿日期:2020-01-06 修回日期:2020-01-09 出版日期:2020-02-25 发布日期:2020-03-16
  • 通讯作者: 李慧萍
  • 基金资助:
     

The intelligence profile of preschool children with autistic spectrum disorders and FSIQ>70: A case-control study

 DENG Jing-xin, YAN Dong-yong, XU Qiong, LI Hui-ping, XU-Xiu   

  1.  Children's Hospital of Fudan University, Shanghai 201102, China
  • Received:2020-01-06 Revised:2020-01-09 Online:2020-02-25 Published:2020-03-16
  • Contact: LI Hui-ping
  • Supported by:
     

摘要: 摘要目的:分析总智商(FSIQ)>70的学龄前期孤独症谱系障碍(ASD)儿童的智力结构,为不同性别ASD儿童的早期干预以及融合教育技术改良提供参考依据。方法:选取2018年8月至2019年12月复旦大学附属儿科医院(我院)ASD数据库中完成第4版中文版韦氏幼儿智力量表[WPPSI-Ⅳ(CN)]且FSIQ >70、4~6岁的全部ASD儿童,根据性别分为男女生两组。行智力水平和智力结构差异性分析。ASD诊断符合DSM-V的ASD诊断标准,ASD诊断观察量表(ADOS)评估分数符合ASD的诊断切点, 由取得WPPSI-Ⅳ(CN)主试资格证书医生行智力评估。结果:24例ASD患儿进入本文分析,男生组20例,女生组4例,年龄49~78(63.9±9.4)月龄;19例患儿在初诊时完成了ADOS评估(男16,女3),21例初诊时完成了父母文化水平的采集,ASD男女生组初诊年龄、智测年龄、ADOS评估、父母文化程度等差异均无统计学意义;FSIQ男生组(88.5±12.2)与女生组 (107.5±12.5)差异有统计学意义(P=0.009);WPPSI-Ⅳ(CN)中男生组视觉空间显著高于工作记忆和加工速度(P均<0.001);女生组不同功能区评估得分差异无统计学意义(P=0.403),不同功能区女生组均高于男生组,言语理解、工作记忆和加工速度差异有意义(P<0.05)。结论:FSIQ>70的ASD女童的智力水平高于男童,男童视觉空间指数显著高于工作记忆指数和加工速度指数,女童言语理解、工作记忆和加工速度较男童有优势。

 

Abstract: Abstract Objective:To explore the intelligence profile of preschool children with autistic spectrum disorders (ASD) and FSIQ>70, hoping to provide reference for early interventions and technological improvements in inclusive education for ASD children. Methods:ASD children aged 4-6 years who received the test of Chinese version of the Wechsler Preschool and Primary Scale of Intelligence-Fourth Edition (WPSSI-Ⅳ(CN)) and got FSIQ>70 were selected from the database of Department of Child Health Care at Children's Hospital of Fudan University. Their intelligence structure and level were analyzed by gender. ASD children were diagnosed according to DSM-V criteria and their scores of Autism Diagnostic Observation Schedule (ADOS) met the diagnostic point of ASD. Intelligence assessment was conducted by qualified doctors who have a certificate of WPSSI-Ⅳ. Results:A total of 24 ASD children (20 boys and 4 girls) aged 49-78 (63.9±9.4) months were included. At the first diagnosis, 19 of them had completed the ADOS assessment (16 boys and 3 girls) and educational levels of 21 children's parents were collected . There were no statistically significant differences between girls and boys in age at the first diagnosis, age of wisdom assessment, ADOS scores and parental education levels, while there were statistically significant differences between boys (88.5±12.2) and girls (107.5±12.5) in FSIQ (P=0.009). Boys had strength in Visual Spatial Index (VSI), while their ability in Working Memory Index (WMI) and Processing Speed Index (PSI) was poorer (P<0.001). There were no statistically significant differences in all functional areas of girls (P=0.043). Girls performed better than boys in all the functional areas, with significant differences in verbal comprehension index (VCI), WMI and PSI (P<0.05). Conclusion:ASD girls with FSIQ>70 had higher intelligence levels than boys. Boys' performance in VSI was significantly better than that in WMI and PSI. Girls had greater advantages than boys in VCI, WMI and PSI.

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